cryptoper

Description

Cryptoper Suspension (Nitazoxanide 100 mg / 5ml) belongs to the class of drugs known as triazolides. Nitazoxanide (NTZ) is a broad-spectrum anti-infective drug that affects the survival, growth, and proliferation of a range of protozoa, helminths, anaerobic bacteria, in addition to viruses. Nitazoxanide is a first-line standard treatment for illness caused by Cryptosporidium parvum or G. lamblia infection in adults and children it is the only molecule effective in diarrhea caused by Rotavirus

Active Ingredient

(Nitazoxanide 100 mg / 5ml) suspension

Mechanism of Action

• • • • The general effect of this medication is the prevention of microbe activity through disruption of important energy pathways for survival and proliferation. Nitazoxanide exhibits antiprotozoal activity by interfering with the pyruvate ferredoxin oxidoreductase dependent electron transfer reaction (PFOR), an essential reaction needs for anaerobic energy metabolism of various microorganisms. Sporozoites of Cryptosporidium parvum and trophozoites of Giardia lamblia are therefore inhibited, relieving symptoms of diarrhea. Interference with the PFOR enzyme-dependent electron transfer reaction may only be one of the many pathways by which nitazoxanide exhibits antiprotozoal activity

Indications & Uses

• Diarrhea caused by Rotavirus
• Diarrhea caused by intestinal protozoa (cryptosporidium, Entamoeba, Giardia)
• Diarrhea caused by anerobic bacteria (H. Pylori, Clostridium difficle)

Dosage & Administration

- Children 1 – 3 years: 5 ml every 12 hrs.

- Children 4 - 11 years 10 ml every 12hrs.

• 3 days only

Forms & Strengths

Bottle 60 ml suspension, Nitazoxanide 100 mg / 5ml

Contraindications & Cautions

• • Hypersensitivity to the active substance, or any of the excipients

Food Interactions Cautions

• • Take with food as food improves oral bioavailability.