D-Clar

D-clar

D-clar (Desloratadine 5mg) is oral disintegrated tablet, Non-sedative H1 antihistamine, used to treat allergies, D-clar has a rapid onset of action, it improves patients quality of life (better sleep & performance in daily activities), cause no drowsiness or sedation, it has a long duration 24 hrs. it is very effective from the 1st dose (improve pruritis score by 45% after 1st dose), effective in relieving nasal congestion, also neither food nor grapefruit juice had an effect on its bioavailability & D-clar has an amazing safety profile

Active Ingredient

Desloratadine, the active metabolite of loratadine

Mechanism of Action

Selective Peripheral H1 Receptor Antagonist Activity (Anti-Histaminic Action), Powerful inhibition of Allergic cascade (Anti-Allergic Effect) and Stabilizes Mast cell & Basophiles, so it inhibits release of acute and chronic inflammatory mediators e.g. Histamine, Leukotriene, PG, Cytokines, Chemokine & Adhesion Molecules (Anti-inflammatory & Decongestant Effect)

Indications & Uses

• - Seasonal Allergic Rhinitis SAR (Hay Fever)
• - Perennial Allergic Rhinitis PAR.
• - Chronic Idiopathic Urticaria CIU (Hives)
• - Angioedema
• - Allergic Conjunctivitis

Dosage & Administration

• - Once daily D-Clar™ ODT for adults and children above 12 years
• - Place D-Clar™ tablet on the tongue and allow for disintegration

Forms & Strengths

A box of 10 oral disintegrated tablet, contains 5 mg of Desloratadine

Contraindications & Cautions

D-clar tablets are contraindicated in patients who are hypersensitive to this medication or to any of its ingredients or to loratadine

Pregnancy & Breastfeeding

Pregnancy category C

There are however, no adequate and well-controlled studies in pregnant women, because animal reproduction studies are not always predictive of human response, desloratadine should be used during pregnancy only if clearly needed

Lactation:
D-clar passes into breast milk, therefore a decision should be made whether to discontinue nursing or to discontinue desloratadine, taking into account the importance of the drug to the mother

F.A.Q

What is D-clar?

D-clar is used to treat symptoms such as watery eyes, sneezing, hives and a runny or blocked nose when in contact with substances such as insect bites, dust mites, pet fur or pollen. The active ingredient desloratadine is considered a non-drowsy antihistamine type of medication that reduces the effect of the natural chemical histamine in the body. It is used to treat perennial allergic rhinitis as well as seasonal allergic reactions

How is D-clar used?

D-clar should be taken orally once per day with or without food unless directed otherwise by a doctor, Place D-clar tablet on the tongue and allow for disintegration

How does D-clar work?

The active substance (desloratadine) is an antihistamine. It works by blocking the receptors to which histamine, a substance in the body that causes allergic symptoms, normally attaches itself. When the receptors are blocked, histamine cannot have its effect, and this leads to a decrease in the symptoms of allergy

What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one

What side effects are possible with D-clar?

In adults and adolescents, the most common side effects are fatigue (tiredness; 1.2%), dry mouth (0.8%) and headache (0.6%). D-clar must not be used in people who are hypersensitive (allergic) to desloratadine, loratadine or any of the other ingredients